The UEFA Champions League Round of 16 second-leg fixtures take place on Tuesday night with several blockbuster encounters deciding who progresses to the quarterfinals. We take a closer look at three of the standout ties from a betting perspective below.
Arsenal vs Bayer Leverkusen – Click here to bet
First Leg Recap
Arsenal travelled to Germany for the opening meeting and returned with a valuable result after playing out a 1-1 draw against Bayer Leverkusen. The Gunners managed to grab an important point and now return to the Emirates Stadium knowing a victory will secure their place in the next round.
Recent Form
Arsenal have been in exceptional form across all competitions in recent weeks. They most recently recorded a 2-0 victory over Everton in the Premier League after edging Brighton 1-0 away from home and beating Mansfield 2-1 in Cup action.
Leverkusen have experienced a more inconsistent spell of results. They shared the spoils with Bayern Munich after a 1-1 stalemate and were involved in an entertaining 3-3 draw away to Freiburg. The German side also claimed a narrow 1-0 victory away to Hamburg recently, highlighting their ability to grind out results.
Head-to-Head
Arsenal hold the historical edge in meetings between the sides. The two clubs have drawn twice, and Arsenal have won the remaining encounters, including a convincing 4-1 success in a friendly in 2024.
Match Odds (1X2)
Arsenal: 1.29
Draw: 6.00
Bayer Leverkusen: 10.00
Verdict
Arsenal have looked extremely sharp in attack while maintaining defensive discipline in recent matches. With home advantage and strong momentum on their side, they should have enough quality to break through Leverkusen and secure progression.
BET: Match Result and Both Teams to Score, Arsenal and No at 2.15

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Chelsea vs Paris Saint-Germain – Click here to bet
First Leg Recap
Paris Saint-Germain delivered a devastating attacking performance in the first leg, defeating Chelsea 5-2 in Paris to take firm control of the tie. That result leaves Chelsea needing a huge comeback at Stamford Bridge if they are to keep their Champions League campaign alive.
Recent Form
Chelsea’s recent results have been mixed across competitions. They suffered a 1-0 home defeat to Newcastle in the league but had previously produced an impressive 4-1 away win over Aston Villa and comfortably defeated Wrexham 4-2 in cup action.
PSG arrive with plenty of confidence following several strong performances. They dismantled Marseille with a dominant 5-0 victory and also secured a comfortable 3-0 success against Metz in Ligue 1. Although they slipped to a 3-1 defeat against Monaco earlier this month.
Head-to-Head
The meetings between these clubs have usually been competitive, though PSG now hold the upper hand following their emphatic first-leg victory. Prior to that they last met in 2025 during the Fifa Club World Cup where Chelsea pulled off a 3-0 triumph.
Match Odds (1X2)
Chelsea: 2.15
Draw: 4.25
PSG: 3.00
Verdict
Chelsea must attack from the first whistle in an attempt to erase the deficit, which could result in an open contest. PSG’s pace and attacking quality mean they remain a major threat on the break, suggesting another entertaining encounter.
BET: Totals Over 3.5 Goals at 2.00
Manchester City vs Real Madrid – Click here to bet
First Leg Recap
Real Madrid seized control of the tie in the first leg at the Santiago Bernabéu where they secured an impressive 3-0 victory over Manchester City. The English powerhouse now face a major challenge as they attempt to get back into the tie at the Etihad Stadium.
Recent Form
Manchester City’s recent form has been slightly inconsistent. They were held to a 1-1 draw away to West Ham in their most recent league outing after settling for a 2-2 draw with Nottingham Forest earlier in the month. However, they also produced a strong 3-1 Cup victory away to Newcastle and edged Leeds with a 1-0 win in the league.
Real Madrid arrive in excellent shape after dismantling Elche with a convincing 4-1 victory and securing a 2-1 away win against Celta Vigo shortly before that. The Spanish giants have regularly unlocked opposition defences in recent weeks while also demonstrating resilience in key European fixtures.
Head-to-Head
These two clubs have developed one of the most exciting rivalries in the Champions League in recent seasons. Real Madrid’s commanding first-leg success added another chapter to their dramatic encounters after City won 2-1 in the group stages in December.
Match Odds (1X2)
Manchester City: 1.51
Draw: 5.00
Real Madrid: 5.75
Verdict
Manchester City will likely dominate possession as they attempt to chase down the deficit but that could leave space open for Real Madrid’s dangerous counterattacks. With both sides possessing tremendous attacking quality, another lively contest looks likely.
I am going to have a bet that with City pressing hard they leave room at the back and Real Madrid core the final goal.
BET: Team to score last goal, Real Madrid at 3.00
Odds correct at time of writing but subject to change.


